2021-22 ND Calendar at a Glance
| August | Monday | 30 | School opens - Freshmen and Transfers only. Starts at 7:45 am |
| Tuesday | 31 | School for Freshmen and Sophomores Only. Starts at 7:45 am | |
| September | Wednesday-Thursday | 1-2 | School for ALL Classes Report by 7:45 am |
| Friday | 3 | School closed for Labor Day | |
| Monday | 6 | School closed for Labor Day | |
| Thursday | 9 | Picture Day | |
| October | Thursday | 7 | National Shrine Trip |
| Monday | 11 | School Closed - Columbus Day | |
| Wednesday | 13 | PSAT | |
| Thursday | 21 | Picture Re-Take | |
| November | Monday | 1 | Second Quarter begins |
| Friday - Saturday | 19-20 | Holiday Play | |
| Wednesday - Monday | 24-29 | School Closed - Thanksgiving Holiday | |
| December | Tuesday | 15 | Christmas Concert |
| Wednesday | 22 | Early Dismissal, 11 am | |
| Thursday - Friday | 23-31 | School Closed - Christmas Holidays | |
| January | Friday | 14 | Mid-Term Exams - Early dismissal 11 am |
| Monday | 17 | School Closed - MLK Day - In-service | |
| Tuesday-Thursday | 18-20 | Mid-Term Exams - Early dismissal 11 am | |
| Friday | 21 | March for Life | |
| Monday | 24 | Third Quarter begins | |
| Sunday-Monday | 30-31 | Catholic Schools Week begins | |
| February | Tuesday-Saturday | 1-5 | Catholic Schools Week continues |
| Friday-Monday | 18-21 | School Closed - Thon | |
| March | Friday | 4 | Pops Concert |
| Monday | 28 | Fourth Quarter begins | |
| April | Friday-Sunday | 8-10 | Spring Musical |
| Thursday-Friday | 14-15 | School Closed - Easter Holiday | |
| Monday | 18 | School Closed - Easter Holiday | |
| May | Tuesday | 10 | Spring Concert |
| Friday | 13 | Prom | |
| Monday | 30 | School Closed - Memorial Day | |
| June | Friday | 3 | Baccalaureate |
| Saturday | 4 | Graduation - 4 pm | |
| Monday - Thursday | 6-9 | Final Exams - Early Dismissal 11 am | |
| Friday | 10 | Last Day of School - Early Dismissal 11:00 am |